Websmarcc2基因编码序列nm_003075.5，smarcc2蛋白编码序列np_003066.2，smarcc2基因又名baf170; cracc2; css8; rsc8,smarcc2基因,smarcc2蛋白,smarcc2抗体,smarcc2表达质粒,smarcc2基因cdna,smarcc2基因crispr质粒,smarcc2基因shrna干扰质粒,smarcc2蛋白,smarcc2抗体,smarcc2抗体,smarcc2表达质粒,smarcc2基因cdna,smarcc2基因crispr质 … Web该基因编码的蛋白质是一种复杂结构的一部分，它解除了抑制性染色质结构，使转录机制能够更有效地访问其目标。编码的核蛋白还可能与hiv-1整合酶结合，并增强其dna连接活性。该基因被发现是一种肿瘤抑制因子，其突变与恶性横纹肌样肿瘤有关。
Expanding the Spectrum of BAF-Related Disorders: De
WebNov 23, 2024 · SMARCC2 knockout promoted the proliferation of glioblastoma cells, while its overexpression showed the opposite effect. Mechanistically, SMARCC2 negatively regulates transcription by dynamically regulating the chromatin structure and closing the promoter region of the target gene DKK1, which can be bound by the transcription factor … WebSep 22, 2024 · Consistently, ITC indicated that the Rpt1 motif binds to SMARCC2 SWIRM with a Kd of ∼ 0.12 μM, a value comparable to one of the two Kd values (0.112 μM) measured for SMARCB1 (169–385 ... hidden pull handles manufacturer
SMARCC2 SWI/SNF related, matrix associated, actin dependent …
WebNov 30, 2024 · Clinical Significance. A change in this gene was identified in a UDN participant and other patients with similar symptoms ( Machol et al. 2024 ). Gene … WebChIP-seq的 数据显示：RFX5 能够结合Cyclin D1 (CCND1)、MYC、CDK4、MDM2 和MDM4等细胞周期调控基因的转录调控区域，提示RFX5 可能参与细胞周期的调控，肝癌中过表达的RFX5 可能通过上调细胞周期相关基因的表达水平，致使细胞周期失调控，进而发展为原发性 … The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Two transcript variants encoding different isofor… hidden publishers